研究成果: |
目前,滕博士已作为项目负责人承担科研项目18项,(其中国家及省部级项目8项),获得经费900余万元;共发表SCI论文140余篇,被引频次1800余次,h因子为24,其中代表性论文发表在Nature Biomedical Engineering,Nano Letters,Nano Today,Biotechnology Advances,ACS Applied Materials & Interfaces,Theranostics,Journal of Controlled Release等杂志上。获授权发明专利24项,其中以第一发明人身份授权8项。获得吉林省自然科学学术成果一等奖1项(排名第一);担任Nature Reviews Clinical Oncology、Nano letters 等20余个SCI杂志审稿人,以客座编辑身份在Dose-Response、Current Pharmaceutical Biotechnolgy等5个SCI杂志组织发表特刊。
代表性SCI论文如下: 1. Zhaogang Yang#, Junfeng Shi#, Jing Xie, Yifan Wang, Jingyao Sun, Tongzheng Liu, Yarong Zhao, Xiuting Zhao, Xinmei Wang, Yifan Ma, Veysi Malkoc, Chiling Chiang, Weiye Deng, Yuanxin Chen, Yuan Fu, Kwang J. Kwak, Yamin Fan, Chen Kang, Changcheng Yin, June Rhee, Paul Bertani, Jose Otero, Wu Lu, Kyuson Yun, Andrew S. Lee, Wen Jiang, Lesheng Teng*, Betty Y. S. Kim * and L. James Lee*, Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation, Nature Biomedical Engineering 2020, 4(1), 69-83.(封面论文) 2. Junyang Wang, Chao Zheng, Yihui Zhai, Ying Cai, Robert J. Lee, Jianming Xing, Hao Wang, Helen H. Zhu, Lesheng Teng*, Yaping Li*, Pengcheng Zhang*, High-density lipoprotein modulates tumor-associated macrophage for chemoimmunotherapy of hepatocellular carcinoma, Nano Today, 2021, 37, 101064. 3. Yujing Li, Jianxun Ding, Xiaoding Xu, Run Shi, Phei Er Saw, Junqing Wang, Shirley Chung, Wenliang Li, Bader M. Aljaeid, Robert J. Lee, Wei Tao, Lesheng Teng*, Omid C. Farokhzad*, Jinjun Shi*, Dual hypoxia-targeting RNAi nanomedicine for precision cancer therapy, Nano Letters 2020, 20, (7), 4857-4863. 4. Junyang Wang, Jia Meng, Robert J. Lee, Lesheng Teng*, Pengcheng Zhang*, Yaping Li*, Hepatocellular carcinoma growth retardation and PD-1 blockade therapy potentiation with synthetic high-density lipoprotein. Nano Letters 2019, 19, (8), 5266-5276.
5. Xiangshi Sun, Kongtong Yu, Yulin Zhou, Shiyan Dong, Wenji Hu, Yating Sun, Yuhuan Li, Jing Xie, Robert J. Lee, Fengying Sun, Yifan Ma, Shengnian Wang, Betty Y. S. Kim, Yifan Wang, Zhaogang Yang, Wen Jiang*, Youxin Li*, Lesheng Teng*, Self-assembled pH-sensitive polymeric nanoparticles for the inflammation-targeted delivery of Cu/Zn-superoxide dismutase, ACS Applied Materials & Interfaces, 2021, 13(15), 18152-18164.(封面论文)
代表性项目: 1. 国家自然科学基金面上项目,具备肿瘤杀伤及逆转肿瘤微环境的载药功能化中性粒细胞的构建及其在非小细胞肺癌治疗中的应用,2021/01-2024/12,56万元,主持 2. 国家自然科学基金青年项目,基于微流控芯片技术制备多功能靶向siRNA脂质纳米粒及其合成机制的研究,2016/01-2018/12,21万元,主持 3. 吉林省科技厅国合项目,共载阿霉素和依帕司他的靶向脂质体的制备及其抑制肿瘤生长及迁移的研究,2020/01-2022/12,20.0万元,主持 4. 吉林省科技厅,用于治疗精神疾病的新颖化合物及其制备方法,2013/01-2015/12,50万元,主持 5. 吉林省发展和改革委员会项目,多西他赛白蛋白纳米粒的研发,2012/01-2014/12,20万元,主持
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