师资队伍

微生物学与免疫学系

孙 栋

日期:2022-02-09 点击数: 来源:必赢电子游戏网站

孙栋

姓名:

孙 栋

职称:

副教授

最高学位:

博士

Email:

dongsun@jlu.edu.cn

工作地点:

生命科学楼409室

研究方向:

焦虑障碍,抑郁症及阿尔茨海默症的发病机制

教育经历:

2012/09–2017/07,    东北师范大学,必赢电子游戏网站,    博士

2015/11–2016/11,    Augusta University(美国),    国家公派联合培养博士

2008/09–2012/07,    东北师范大学,必赢电子游戏网站,    学士

工作经历:

2021/09–至今,         bwin必赢登录入口官网,必赢电子游戏网站,                             副教授

2017/11–2021/03,   Case Western Reserve University (美国),   博士后

荣誉称号:

2022年入选“bwin必赢登录入口官网唐敖庆青年学者”; 2021年获得“bwin必赢登录入口官网唐敖庆青年人才奖励基金”

研究成果:

       课题组利用小鼠为模式生物,结合化学遗传方法,脑立体定位注射,病毒环路示踪,行为学测试,高通量测序,细胞及分子生化等技术手段研究焦虑障碍,抑郁症及阿尔茨海默症的发病机制。先后在Biol. Psychiatry, PNAS, Cell Death & Disease, J. Neuroscience等知名期刊发表学术论文20余篇,主持或参与多项国家和省部级科研项目。

主持科研项目:

1. 国家自然科学基金青年科学基金项目,项目编号:32200824,2023/01-2025/12,30万,主持

2. 科技创新2030-“脑科学与类脑研究”重大项目青年科学家项目,项目编号:2022ZD0214300,2022/08-2027/07,70万,项目骨干

3. 吉林省科技厅青年成长科技计划项目,项目编号:20220508067RC,2022/07-2024/06,12万,主持

代表性期刊论文:

1. Dong Sun,Lin Mei, and Wen-Cheng Xiong* (2023) Dorsal Dentate Gyrus, a Key Regulator for Mood and Psychiatric Disorders.Biological Psychiatry (中科院1区,IF2022= 10.6)

2. Dong Sun#,Zhi-Bing Tan#, Xiang-Dong Sun, Zhi-Peng Liu, Wen-Bing Chen, Leena Milibari, Xiao Ren, Ling-Ling Yao, Daehoon Lee, Chen Shen, Jin-Xiu Pan, Zhi-Hui Huang, Lin Mei, and Wen-Cheng Xiong*. (2021) Hippocampal astrocytic neogenin regulating glutamate uptake, a critical pathway for preventing epileptic response.PNAS (中科院1区,IF2021= 12.78) (#, equal contribution)

3.Dong Sun, Leena Milibari, Jin-Xiu Pan, Xiao Ren, Ling-Ling Yao, Yang Zhao, Chen Shen, Wen-Bing Chen, Fu-Lei Tang, Daehoon Lee, Jun-Shi Zhang, Lin Mei, Wen-Cheng Xiong*. (2021) Critical roles of embryonic born dorsal dentate granule neurons for activity-dependent increases in BDNF, adult hippocampal neurogenesis, and anti-anxiety-like behaviors.Biological Psychiatry (中科院1区,IF2021= 12.81)

4.Dong Sun, Xiang-Dong Sun, Lu Zhao, Dae-Hoon Lee, Jin-Xia Hu, Fu-Lei Tang, Jin-Xiu Pan, Lin Mei, Xiao-Juan Zhu*, Wen-Cheng Xiong*. (2018) Neogenin, a regulator of adult hippocampal neurogenesis, prevents depressive-like behavior.Cell Death & Disease (中科院2区,IF2018= 5.96)

5. Jin-Xiu Pan#,Dong Sun#,Daehoon Lee, Lei Xiong, Xiao Ren, Hao-han Guo, Ling-ling Yao, Yuyi Lu, Caroline Jung, Wen-Cheng Xiong*. (2021) Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence.Communications Biology (中科院1区,IF2021= 6.55) (#, equal contribution)

6. Xiang-Dong Sun#*, Wen-Bing Chen#,Dong Sun#,Jie Huang, Yuan-Quan Li, Jin-Xiu Pan, Ya-Nan Wang, Kai Zhao, Zhao-Qi Dong, Hong-Sheng Wang, Lei Xiong, Aiguo Xuan, Shen-Ting Zhao, Anilkumar Pillai, Wen-Cheng Xiong* and Lin Mei. (2018) Neogenin in Amygdala for Neuronal Activity and Information Processing.Journal of Neuroscience (中科院1区,IF2018= 6.07) (#, equal contribution)

7.Dong Sun, Xue Zhou, Hua-Li Yu, Xiao-Xiao He, Wei-Xiang Guo, Wen-Cheng Xiong*, Xiao-Juan Zhu*. (2017) Regulation of neural stem cell proliferation and differentiation by Kinesin family member 2a.PLoS ONE (中科院3区,IF2017=2.77 )